124. Challenges in Understanding the Causes and Consequences of Obesity

Obesity reflects a preceding slow cumulative positive energy balance.
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Obesity reflects a preceding slow cumulative positive energy balance.
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Obesity reflects a preceding slow cumulative positive energy balance. Whether it is primarily due to a minutely increased input, decreased expenditure or increased deposition remains unclear. Obesity leads to increased energy expenditure and hence increased energy needs, making it difficult to distinguish the processes and a challenge to interfere. Genetic predisposition and environmental exposures are involved, but which specific factors are operating and when remain to be clarified. The strong association between psycho-socio-economic factors and obesity calls for a new theory. Obesity is associated with metabolic alterations predisposing to several diseases, with diabetes and cardiovascular diseases as the most prominent. However, some of the obese escape the problems, whereas some skinny fat may suffer from them. The link between the accumulation of the excess though inert triglyceride in fat cells and the metabolic alterations may be explained by the adipose expandability theory.
CPEU: 1.5
CPE Level: 3
Learning Codes: 5370, 2050, 3040
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