191. Clinical Insight into Vitamin B12

FNCE Recorded Sessions from 2017

New research shows that B12 deficiency is a worldwide problem.

  • Release Date: October 22, 2017
  • SKU FNCE17191
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This product is free for those who attended FNCE® 2017.

It was once thought that vitamin B12 (B12) deficiency is extremely rare and found only among some vegans. New research shows that B12 deficiency is a worldwide problem. It is now known patients with diabetes, atrophic gastritis, the MTHFR C677T genetic mutation, irritable bowel disease, patients with surgery with general anesthesia, AIDS, chemotherapy, or hypothyroidism, among other conditions, develop B12 deficiency, along with vegetarians and the elderly. Hundreds of new publications describing new insights regarding the role of B12 status in disease development are published every year. Unless, one specializes in the narrow field of B12 research, a clinician is not able to keep up with all the new findings. Unfortunately, this leads to holding on to old myths and assumptions and missing out on making proper assessment of B12 status. This lecture will provide an update on how to recognize B12 deficiency, assess and interpret B12 status and overview treatment options.

CPEU: 1.5
CPE Level: 3
Learning Codes: 2090, 3010, 3005

Learning Objectives

  • List groups of individuals at risk of vitamin B12 deficiency
  • Describe differences between different vitamin B12 assessment methods (serum B12, MCV, homocysteine, Holo-TCII, methylmalonic acid)
  • Describe the differences in vitamin B12 treatment options, doses, routes of administrations, effectiveness of injections vs. supplements, cyanocobalamin, methylcobalamin, hydroxocobalamin


  • Roman Pawlak, PhD, RDN,


  • Wahida Karmally, Dr.PH,RDN,CDE,CLS,FNLA
  • Release Date: October 22, 2017
  • SKU FNCE17191