BHN Newsletter - Probiotics for Depression and Anxiety: Emerging Mechanisms and Considerations for Clinical Application

BHN Newsletter

This article reviews the hypothesis that increased prevalence of anxiety and depressive disorders can be attributed, in part, to a decrease in microbial diversity fueled by modern food choices.

  • Release Date: January 28, 2019
  • SKU NSCBHNNPDAEMCCA
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This article was produced in collaboration with The Integrative RDN, a publication of Dietitians in Integrative and Functional Medicine DPG

The microbiota-gut-brain axis has been explored broadly for its role in behavior and the mind, including pain perception, cognitive function, mood and emotion, temperament, stress management, and even social interaction. In the Journal of Physiological Anthropology, Selhub, Logan, and Bested hypothesize that increased prevalence of anxiety and depressive disorders can be attributed, in part, to a decrease in microbial diversity fueled by modern food choices such as decreased intake of dietary fibers acting as microbiota-accessible carbohydrates, citing population studies which link traditional healthy diets (such as Mediterranean or Japanese) with lower risk of anxiety or depression. Skillful application of therapeutic lifestyle interventions which strategically modify the microbiome, even if modifications are transient in nature, holds potential to address the significant burden of anxiety and depressive disorders.

CPEU: 1.0
CPE Level: 2
Learning Need Codes: 5420, 4040, 5320
Performance Indicators: 10.4.1, 8.1.5, 8.3.1

Learning Objectives

  1. Differentiate psychobiotics from probiotics
  2. Identify three central nervous system mediated mechanisms through which the microbiome could impact mental health and wellbeing
  3. Summarize clinical measurement tools used in research settings to evaluate clinical response to trials using psychobiotics

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  • Release Date: January 28, 2019
  • SKU NSCBHNNPDAEMCCA